SHP1 (Ser-591), phospho-specific Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SHP1 (Ser-591), phospho-specific |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody was cross-adsorbed to a non-specific phospho-serine peptide then affinity-purified using phospho-SHP1 (Ser-591) peptide. The antibody detects a 68 kDa* band on SDS-PAGE immunoblots of human Jurkat and A431 cells treated with pervanadate, as wellas A431 cells treated with EGF. SHP1 (PTP1C, SH-PTP1, or HCP) is a protein-tyrosine phosphatase (PTP) involved in cell migration, cell proliferation, and immune cell function. This phosphatase contains two N-terminal SH2 domains and a C-terminal phosphatase domain. SHP1 associates with a variety of cytokine and growth factor receptors and regulates signal transduction through dephosphorylation of these receptors or their downstream effectors. Downstream of receptor activation, SHP1 regu |
| Immunogen | Immunogen: Phospho-SHP1 (Ser-591) synthetic peptide (coupled to carrier protein) corresponding to amino acids around serine 591 in human SHP1. Thesequence is highly conserved in rat and mouse SHP1. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS472061 |
| Price | $385 |
| Order / More Info | SHP1 (Ser-591), phospho-specific Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Jones, M.L. et al. (2004) J. Biol. Chem. 279(39):40475.• Zhang, Z. et al. (2003) J. Biol. Chem. 278(7):4668.• Zhang, J. et al. (2000) Semin. Immunol. 12:361.• Simoneau, M. et al. (2008) J Biol Chem Epub:July 10. (WB: S591A transfectants) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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