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Antigenic Specificity | Phospho-PYK2-Y402 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y402 of human Pyk2 |
Other Names | [protein-tyrosine kinase 2-beta isoform a; Protein-tyrosine kinase 2-beta; protein-tyrosine kinase 2-beta; protein tyrosine kinase 2 beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Proline-rich tyrosine kinase 2; Related adhesion focal tyrosine kinase] |
Gene, Accession # | [PYK2], Gene ID: 2185, NCBI: NP_004094.3, UniProt: Q14289 |
Catalog # | MBS8574576 |
Price | $280 |
Order / More Info | Phospho-PYK2-Y402 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |