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Antigenic Specificity | USP8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect USP8 in human samples. Background: Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzyme (DUB) action. Five DUB subfamilies are recognized, including the USP, UCH, OTU, MJD, and JAMM enzymes. The deubiquitinating enzyme ubiquitin-specific protease 8 (USP8/UBPy) is a cysteine protease belonging to the USP/UBP subfamily. Research studies have shown that USP8 is an essential growth-regulated enzyme indispensible for cell proliferation and survival. Indeed, conditional knock-out of murine USP8 was shown to promote a dramatic loss in expression of receptor tyrosine kinases, including EGFR, ErbB3, and c-Met. In agreement with these findings, USP8 inac |
Immunogen | Immunogen: Synthetic peptide corresponding to an internal sequence of human USP 8 (BV-L43). Positive Control: Western blot: Jurkat Cell lysate |
Other Names | [Deubiquitinating enzyme 8; hUBPy; HumORF8; KIAA0055; MGC129718; Ubiquitin carboxyl-terminal hydrolase 8; Ubiquitin-specific processing protease 8; Ubiquitin thioesterase 8; UBP; Ubiquitin Specific Protease 8.], [USP8; USP8; UBPY; SPG59; HumORF8; KIAA0055; UBPY; hUBPy] |
Gene, Accession # | [USP8], Gene ID: 9101, NCBI: NP_001122082.1, UniProt: P40818 |
Catalog # | MBS840297 |
Price | $150, $305 |
Order / More Info | USP8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |