USP8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityUSP8
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionPolyclonal Antibody to detect USP8 in human samples. Background: Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzyme (DUB) action. Five DUB subfamilies are recognized, including the USP, UCH, OTU, MJD, and JAMM enzymes. The deubiquitinating enzyme ubiquitin-specific protease 8 (USP8/UBPy) is a cysteine protease belonging to the USP/UBP subfamily. Research studies have shown that USP8 is an essential growth-regulated enzyme indispensible for cell proliferation and survival. Indeed, conditional knock-out of murine USP8 was shown to promote a dramatic loss in expression of receptor tyrosine kinases, including EGFR, ErbB3, and c-Met. In agreement with these findings, USP8 inac
ImmunogenImmunogen: Synthetic peptide corresponding to an internal sequence of human USP 8 (BV-L43). Positive Control: Western blot: Jurkat Cell lysate
Other Names[Deubiquitinating enzyme 8; hUBPy; HumORF8; KIAA0055; MGC129718; Ubiquitin carboxyl-terminal hydrolase 8; Ubiquitin-specific processing protease 8; Ubiquitin thioesterase 8; UBP; Ubiquitin Specific Protease 8.], [USP8; USP8; UBPY; SPG59; HumORF8; KIAA0055; UBPY; hUBPy]
Gene, Accession #[USP8], Gene ID: 9101, NCBI: NP_001122082.1, UniProt: P40818
Catalog #MBS840297
Price$150, $305
Order / More InfoUSP8 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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