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Antigenic Specificity | NGFR (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This NGFR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 276-310 amino acids from the C-terminal region of human NGFR. Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD271; NGFR; TNFRSF16] |
Gene, Accession # | [NGFR], Gene ID: 4804, NCBI: NP_002498.1, UniProt: P08138 |
Catalog # | MBS9215684 |
Price | $165, $370 |
Order / More Info | NGFR (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Johnson D.,et al.Cell 47:545-554(1986).Ota T.,et al.Nat. Genet. 36:40-45(2004).Zody M.C.,et al.Nature 440:1045-1049(2006).Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.Sehgal A.,et al.Mol. Cell. Biol. 8:3160-3167(1988). |