GCK (Glucokinase) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGCK (Glucokinase)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.25 mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
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DescriptionBackground: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in the gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), also called maturity onset diabetes of the young, type 2 (MODY2); mutations have also been associated with persistent hyperinsulinemic hypoglycemia of
ImmunogenImmunogen: Synthetic peptide selected from the N-terminal region of human GCK
Other Names[Hexokinase D; Hexokinase type IV; HK IV; HK4; Glucokinase], [GCK; GCK; GK; GLK; HK4; HHF3; HKIV; HXKP; LGLK; MODY2; FGQTL3; HK IV; HK4]
Gene, Accession #Gene ID: 2645, NCBI: NP_000153.1, UniProt: P35557
Catalog #MBS840334
Price$375
Order / More InfoGCK (Glucokinase) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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