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Antigenic Specificity | FOXO1 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FOXO1 Antibody detects endogenous levels of total FOXO1. This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Interacts with LRPPRC. Interacts with RUNX2; the interaction inhibits RUNX2 transcriptional activity and mediates the IGF1/insulin-dependent BGLAP expression in osteoblasts Interacts with PPP2R1A; the interaction regulates the dephosphorylation of FOXO1 at Thr-24 and Ser-256 leading to its nuclear import. |
Immunogen | Immunogen: A synthetic peptide of human FOXO1 |
Other Names | [FKH1; FKHR; FOXO1A] |
Gene, Accession # | [FOXO1], Gene ID: 2308, NCBI: NP_002006.2, UniProt: Q12778 |
Catalog # | MBS8516552 |
Price | $290 |
Order / More Info | FOXO1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |