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Antigenic Specificity | Crk-L (Phospho Tyr207) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Crk-L (Y207) Polyclonal Antibody detects endogenous levels of Crk-L protein only when phosphorylated at Y207. CRKL encodes a protein kinase (CRK like proto-oncogene, adaptor protein) containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic. |
Immunogen | Immunogen: Synthesized peptide derived from human Crk-L around the phosphorylation site of Y207 |
Other Names | [Rabbit Crk-L (phospho Tyr207); Crk-like protein] |
Gene, Accession # | [CRKL], Gene ID: 1399, NCBI: NP_005198.1, UniProt: P46109 |
Catalog # | MBS9701256 |
Price | $130, $220, $325 |
Order / More Info | Crk-L (Phospho Tyr207) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |