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Antigenic Specificity | Amphiphysin II |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Amphiphysin II Polyclonal Antibody detects endogenous levels of Amphiphysin II protein. BIN1 encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene result |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human Amphiphysin II |
Other Names | [Rabbit Amphiphysin II; BIN1; AMPHL; Myc box-dependent-interacting protein 1; Amphiphysin II; Amphiphysin-like protein; Box-dependent myc-interacting protein 1; Bridging integrator 1] |
Gene, Accession # | Gene ID: 274, NCBI: O00499.1, UniProt: O00499 |
Catalog # | MBS9703704 |
Price | $130, $220, $325 |
Order / More Info | Amphiphysin II Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |