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Antigenic Specificity | TFEB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobuli |
Immunogen | Immunogen: TFEB antibody was raised in rabbit using a synthetic peptide corresponding to a region within amino acids 1 and 44 of TFEB |
Other Names | [Affinity Purified Rabbit TFEB; TFEB; TFEB; BHLHE35; transcription factor EB; class E basic helix-loop-helix protein 35; alphaTFEB; TFEB; TCFEB; T-cell transcription factor EB] |
Gene, Accession # | [TFEB], Gene ID: 7942, UniProt: P19484 |
Catalog # | MBS5311986 |
Price | $485 |
Order / More Info | TFEB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |