TFEB Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTFEB
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionTranscription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobuli
ImmunogenImmunogen: TFEB antibody was raised in rabbit using a synthetic peptide corresponding to a region within amino acids 1 and 44 of TFEB
Other Names[Affinity Purified Rabbit TFEB; TFEB; TFEB; BHLHE35; transcription factor EB; class E basic helix-loop-helix protein 35; alphaTFEB; TFEB; TCFEB; T-cell transcription factor EB]
Gene, Accession #[TFEB], Gene ID: 7942, UniProt: P19484
Catalog #MBS5311986
Price$485
Order / More InfoTFEB Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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