ULBP1 Antibody from MYBIOSOURCE INC.
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| Edit | |
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| Antigenic Specificity | ULBP1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Ligand for the KLRK1/NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. |
| Immunogen | Immunogen: Recombinant Human NKG2D ligand 1 protein (26-216AA) |
| Other Names | [NKG2D ligand 1; N2DL-1; NKG2DL1; ALCAN-beta; Retinoic acid early transcript 1I; UL16-binding protein 1; ULBP1; N2DL1; RAET1I] |
| Gene, Accession # | [ULBP1], Gene ID: 80329, NCBI: NP_001304018.1, UniProt: Q9BZM6 |
| Catalog # | MBS7106325 |
| Price | $160, $235 |
| Order / More Info | ULBP1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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