VPS35 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | VPS35 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The CSC seems to associate with the cytoplasmic domain of cargo proteins predominantly via VPS35; however, these interactions seem to be of low affinity and retromer SNX proteins may also contribute to cargo selectivity thus questioning the classical function of the CSC. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) |
| Immunogen | Immunogen: Recombinant human Vacuolar protein sorting-associated protein 35 protein (N-250AA) |
| Other Names | [Vacuolar protein sorting-associated protein 35; hVPS35; Maternal-embryonic 3; Vesicle protein sorting 35; VPS35; MEM3; TCCCTA00141] |
| Gene, Accession # | [VPS35], Gene ID: 55737, NCBI: NP_060676.2, UniProt: Q96QK1 |
| Catalog # | MBS7046183 |
| Price | $120, $160 |
| Order / More Info | VPS35 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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