GRIA2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGRIA2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration1.1 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total GRIA2 protein. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for b
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human glutamate receptor, ionotropic, AMPA 2
Other Names[GLUR2; GLURB; GluA2; HBGR2; GluR-K2]
Gene, Accession #[GRIA2], Gene ID: 2891, NCBI: NP_000817.2, UniProt: P42262
Catalog #MBS9407782
Price$255
Order / More InfoGRIA2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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