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Antigenic Specificity | TCF7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TCF7 antibody detects endogenous levels of total TCF7. Description: The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene.Function: Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ CD8+ immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocy |
Immunogen | Immunogen: A synthetic peptide of human TCF7 Subcellular Location: Nucleus. Tissue Specificity: Predominantly expressed in T-cells. Also detected in proliferating intestinal epithelial cells and in the basal epithelial cells of mammary gland epithelium. |
Other Names | [FLJ36364; MGC47735; OTTHUMP00000159391; T cell factor 1; T cell specific transcription factor 1; T-cell factor 1; T-cell-specific transcription factor 1; TCF-1; TCF-7; TCF1; Tcf7; TCF7 transcription factor 7; TCF7_HUMAN; Transcription factor 7 (T cell specific HMG box); Transcription factor 7; Transcription factor-7, T-cell specific; Transcription factor-7, T-cell specific, 1] |
Gene, Accession # | [TCF7], Gene ID: 6932, NCBI: NP_001128323.2, UniProt: P36402 |
Catalog # | MBS9607828 |
Price | $240, $280 |
Order / More Info | TCF7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |