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Antigenic Specificity | DDIT3, 82-110 |
Clone | [563CT2.4.1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DDIT3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from human DDIT3. This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alt |
Immunogen | n/a |
Other Names | [DNA damage-inducible transcript 3 protein; DDIT-3; C/EBP zeta; C/EBP-homologous protein; CHOP; C/EBP-homologous protein 10; CHOP-10; CCAAT/enhancer-binding protein homologous protein; Growth arrest and DNA damage-inducible protein GADD153; DDIT3; CHOP; CHOP10; GADD153] |
Gene, Accession # | [DDIT3], Gene ID: 1649, NCBI: NP_001181982.1, UniProt: P35638 |
Catalog # | MBS9200545 |
Price | $370 |
Order / More Info | DDIT3, 82-110 Antibody from MYBIOSOURCE INC. |
Product Specific References | Park, S.H., et al. J. Immunol. 185(9):5522-5530(2010) Goodall, J.C., et al. Proc. Natl. Acad. Sci. U.S.A. 107(41):17698-17703(2010) Zhang, H.M., et al. J. Virol. 84(17):8446-8459(2010) Cazanave, S.C., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (1), G236-G243 (2010) : Wang, Y.L., et al. J. Exp. Clin. Cancer Res. 29, 54 (2010) |