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Antigenic Specificity | Rat Podoplanin |
Clone | [IgG1, LF3(B7)D5B3] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot, IHC/IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Podoplanin, also known as glycoprotein 36 (gp36), PA2.26 antigen, T1-alpha (T1A), and aggrus, is a 36 kDa type I transmembrane sialoglycoprotein and member of the Podoplanin family. Podoplanin has three potential splice variants, the longest of which is represented by a 238 amino acid precursor. It contains an undefined signal sequence, a 22 aa transmembrane segment (aa 207-228) and a short cytoplasmic tail (aa 229-238). The cytoplasmic tail contains putative sites for protein kinase C phosphorylation. There are two potential alternate start sites at Met 77 (Swiss Prot #: Q86YL7) and Met 119 (EAW51692) that generate short forms. The 162 aa short form Podoplanin precursor shares 47% aa identity with mouse Podoplanin. Podoplanin is expressed |
Immunogen | Immunogen: membrane protein fraction of isolated rat glomeruli. Preparation: Monoclonal antibodies were produced with the help of BALB/c mice using a membrane protein fraction of isolated rat glomeruli as the immunizing antigen. |
Other Names | [rat Podoplanin (#LF3(B7)D5B3); Glycoprotein 36; GP36; T1-alpha; PA2.26 antigen], [Pdpn; Pdpn; E11; Gp38; OTS-8; RTI40; T1-alpha; Gp38; Ots8; Gp38; T1A] |
Gene, Accession # | Gene ID: 54320, NCBI: NP_062231.1, UniProt: Q64294 |
Catalog # | MBS690143 |
Price | $345 |
Order / More Info | Rat Podoplanin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Zimmer et al, Biochem J 341:277, 1999 2. KatsueInoue et al, J Biol Chem 282:25993, 2007 3. Kato et al, J Biol Chem 278:51599, 2003 4. Schacht et al, Am J Pathol 166:913, 2005 5. Breiteneder-Geleff et al, Am J Pathol 151:1141, 1997 6. Kato et al, Tumour Biol 26:195, 2005 7. Kato et al, Oncogene 23:8552, 2004 8. Mishima et al, Acta Neuropathol 111:563, 2006 9. Mishima et al, Acta Neuropathol 111:483, 2006 10. Kato et al, Biochem Biophys Res Commun 349:1301, 2006 |