VWA5A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityVWA5A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentration2.2mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionVWA5A (von Willebrand factor A domain containing 5A), also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein), is a 786 amino acid protein containing one VIT domain and one VWFA domain. VWA5A is expressed at low levels in various tissues, with no expression found in 80% of tumor cell lines. Likely acting as a tumor suppressor gene, deletion of VWA5A leads to loss of heterozygosity (LOH) in breast and ovarian tumors, and may have an important role as a potential gene therapy target. Abnormal expression of VWA5A may lead to an increase in adhesion of CNE-2L2 cells associated with an increase in expression of E-cadherin, alpha-catenin, and p53, resulting in a decr
ImmunogenImmunogen: Recombinant protein of human VWA5A Calculated Molecular Weight: 86kDa
Other Names[BCSC1; BCSC-1; LOH11CR2A]
Gene, Accession #[VWA5A], Gene ID: 4013, NCBI: O00534.2
Catalog #MBS2525379
Price$110, $150, $225
Order / More InfoVWA5A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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