KLF8 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | KLF8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: KLF8 antibody detects endogenous levels of total KLF8. Function: Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G1 phase as a downstream target of focal adhesion kinase (FAK).Subunit Structure: Interacts with corepressor CtBP2. Interacts with PIAS1, PIAS2, AND PIAS4; the interaction with each ligase sumoylates KLF8.Post-translational Modifications: Sumoylation at Lys-67 represses transcriptional activity and reduces cell cycle progression into the G1 phase. Has no effect on subcellular location.Similarity: Belongs to the Sp1 C2H2-type zinc-finger protein family. |
| Immunogen | Immunogen: A synthesized peptide derived from human KLF8 Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Pig, Horse, Rabbit Similarity: Pig (90%), Horse (80%), Rabbit (90%) |
| Other Names | [Basic krueppel-like factor 3; BKLF3; DXS741; KLF8; KLF8_HUMAN; Krueppel-like factor 8; Kruppel like factor 8; MGC138314; Zinc finger protein 741; ZNF741] |
| Gene, Accession # | [KLF8], Gene ID: 11279, NCBI: NP_001152768.1, UniProt: O95600 |
| Catalog # | MBS9609086 |
| Price | $240, $280 |
| Order / More Info | KLF8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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