Human CATHEPSIN B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CATHEPSIN B
Clonepolyclonal
Host SpeciesSheep
Reactive Speciesn/a
Isotypen/a
Formatperoxidase (HRP) conjugate
Size1 mL
ConcentrationIgG concentration 1.0mg/ml
ApplicationsELISA (EIA)
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DescriptionSheep anti Human cathepsin B antibody detects cathepsin B, a lysosomal cysteine protease which functions as both a endopeptidase and a carboxypeptidase. Together with cathepsins D and L, cathepsin B is one of the most abundant proteases in the lysosome, and participates in intracellular protein degradation. Cathepsin B is thought to play an increasingly important role in apoptosis and its release from the lysosome under cell stress leads to Bid cleavage, cytochrome C release and nuclear fragmentation. Cathepsin B is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete processing of APP is thought to be a causative factor in Alzheimer disease. Over-expr
ImmunogenImmunogen: Native cathepsin B from placenta Buffer Solution: Phosphate buffered saline Target Species: Human
Other Names[cathepsin B preproprotein; Cathepsin B; cathepsin B; APP secretase; amyloid precursor protein secretase; cathepsin B1; cysteine protease; cathepsin B; APP secretase; APPS; Cathepsin B1Cleaved into the following 2 chains:Cathepsin B light chain; Cathepsin B heavy chain], [CTSB; CTSB; APPS; CPSB; CPSB; APPS]
Gene, Accession #Gene ID: 1508, NCBI: NP_001899.1, UniProt: P07858
Catalog #MBS223750
Price$370
Order / More InfoHuman CATHEPSIN B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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