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Antigenic Specificity | Human CATHEPSIN B |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | n/a |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 1 mL |
Concentration | IgG concentration 1.0mg/ml |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Sheep anti Human cathepsin B antibody detects cathepsin B, a lysosomal cysteine protease which functions as both a endopeptidase and a carboxypeptidase. Together with cathepsins D and L, cathepsin B is one of the most abundant proteases in the lysosome, and participates in intracellular protein degradation. Cathepsin B is thought to play an increasingly important role in apoptosis and its release from the lysosome under cell stress leads to Bid cleavage, cytochrome C release and nuclear fragmentation. Cathepsin B is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete processing of APP is thought to be a causative factor in Alzheimer disease. Over-expr |
Immunogen | Immunogen: Native cathepsin B from placenta Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [cathepsin B preproprotein; Cathepsin B; cathepsin B; APP secretase; amyloid precursor protein secretase; cathepsin B1; cysteine protease; cathepsin B; APP secretase; APPS; Cathepsin B1Cleaved into the following 2 chains:Cathepsin B light chain; Cathepsin B heavy chain], [CTSB; CTSB; APPS; CPSB; CPSB; APPS] |
Gene, Accession # | Gene ID: 1508, NCBI: NP_001899.1, UniProt: P07858 |
Catalog # | MBS223750 |
Price | $370 |
Order / More Info | Human CATHEPSIN B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |