CLOCK Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CLOCK |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Clock antibody detects endogenous levels of total Clock. Description: CLOCK ARNTL/2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. Activates transcription of PER1 and PER2. This transcription is inhibited in a feedback loop by PER and CRY proteins. Has intrinsic histone acetyltransferase activity and this enzymatic function contributes to chromatin-remodeling events implicated in circadian control of gene expression. Acetylates primarily histones H3 and H4.Function: Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the gen |
| Immunogen | Immunogen: A synthesized peptide derived from human Clock Subcellular Location: Cytoplasm. Nucleus. Shuffling between the cytoplasm and the nucleus is under circadian regulation and is ARNTL-dependent. Phosphorylated form located in the nucleus. Tissue Specificity: Hair follicles (at protein level). Expressed in all tissues examined including spleen, thymus, prostate, testis, ovary, small intestine, colon, leukocytes, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Hig |
| Other Names | [bHLHe8; Circadian locomoter output cycles kaput protein; Circadian locomoter output cycles protein kaput; Circadian Locomotor Output Cycles Kaput; Circadium Locomotor Output Cycles Kaput; Class E basic helix-loop-helix protein 8; CLOCK; Clock circadian regulator; Clock homolog; Clock protein; CLOCK_HUMAN; hCLOCK; KIAA0334] |
| Gene, Accession # | [CLOCK], Gene ID: 9575, NCBI: NP_001254772.1, UniProt: O15516 |
| Catalog # | MBS9600258 |
| Price | $240, $280 |
| Order / More Info | CLOCK Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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