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Antigenic Specificity | STAT5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 0.5 mg/ml |
Applications | Immunoprecipitation (IP), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti STAT5B antibody recognizes signal transducer and activator of transcription 5B (STAT5B), a member of the STAT protein family, which plays an important role in cell growth, survival differentiation and transformation, transducing signals from cytokine receptors to the nucleus. STAT5B is tyrosine phosphorylated by members of the Janus kinase family in response to cytokines and growth factor stimulation. Phosphorylation results in STAT activation and the formation of STAT5 homo- and STAT5/STAT3 heterodimers. STAT dimers translocate from the cytoplasm to the nucleus where they act as transcription factors. Deregulated JAK/STAT signaling has been implicated in a variety of cancers; STATs can regulate the tumor microenvironment and tr |
Immunogen | n/a |
Other Names | [Signal transducer and activator of transcription 5B; Signal transducer and activator of transcription 5B; signal transducer and activator of transcription 5B; signal transducer and activator of transcription 5B], [STAT5B; STAT5B; STAT5] |
Gene, Accession # | [STAT5], Gene ID: 6777, NCBI: P51692.2, UniProt: P51692 |
Catalog # | MBS224948 |
Price | $375 |
Order / More Info | STAT5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |