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Antigenic Specificity | Phospho-TDP43 (Ser409) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: zebrafish, dog, chicken |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-TDP43 (Ser409) Antibody detects endogenous levels of TDP43 only when phosphorylated at Ser409. Description: DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.Pos |
Immunogen | Immunogen: A synthesized peptide derived from human TDP43 around the phosphorylation site of Ser409. Tissue Specificity: Ubiquitously expressed. In particular, expression is high in pancreas, placenta, lung, genital tract and spleen. |
Other Names | [ALS10; OTTHUMP00000002171; OTTHUMP00000002172; OTTHUMP00000002173; TADBP_HUMAN; TAR DNA binding protein 43; TAR DNA binding protein; TAR DNA-binding protein 43; TARDBP; TDP 43; TDP-43; TDP43] |
Gene, Accession # | [TDP43], Gene ID: 23435, NCBI: NP_031401.1, UniProt: Q13148 |
Catalog # | MBS9610727 |
Price | $225, $280, $340 |
Order / More Info | Phospho-TDP43 (Ser409) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |