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Antigenic Specificity | UBXN1 - C-terminal |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against UBXN1. It was validated on Western BlotTarget Description: UBXN1 is a ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. It specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, it leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. It is a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human UBXN1 |
Other Names | [UBX domain-containing protein 1 isoform 1; UBX domain-containing protein 1; UBX domain-containing protein 1; UBX domain protein 1; SAPK substrate protein 1; UBA/UBX 33.3 kDa protein] |
Gene, Accession # | [UBXN1], Gene ID: 51035, NCBI: NP_056937, UniProt: Q04323 |
Catalog # | MBS3220057 |
Price | $335 |
Order / More Info | UBXN1 - C-terminal Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |