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Antigenic Specificity | Mono-methyl-Histone H3 / Lys4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Histones are the basic nuclear proteins responsible for the nucleosome structure within the chromosomal fiber in eukaryotes. Five classes of histone genes have been reported, Histone H3 is one of them.[1] Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones. It is an important protein in the emerging field of epigenetics, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes.[2] |
Immunogen | Immunogen: A synthetic peptide (conjugated to KLH) corresponding to the region of Mono-methyl-Histone H3. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS355139 |
Price | $275 |
Order / More Info | Mono-methyl-Histone H3 / Lys4 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Bhasin M, Reinherz EL, Reche PA (2006). Recognition and classification of histones using support vector machine. J. Comput. Biol. 13 (1): 102-12. 2. Fischle, W., Tseng, B. S., Dormann, H. L., Ueberheide, B. M., Garcia, B. A., Shabanowitz, J., Hunt, D. F., Funabiki, H., Allis, C. D. Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature 438: 1116-1122, 2005 |