AANAT Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAANAT
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration2.4 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total AANAT protein. The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human aralkylamine N-acetyltransferase
Other Names[DSPS; SNAT]
Gene, Accession #[AANAT], Gene ID: 15, NCBI: NP_001079.1, UniProt: Q16613
Catalog #MBS9411433
Price$255
Order / More InfoAANAT Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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