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Antigenic Specificity | Phospho-KSR1 (Ser569) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, bovine, rabbit, dog |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-KSR1 (Ser569) Antibody detects endogenous levels of KSR1 only when phosphorylated at Ser569. Description: Scaffolding protein that is part of a multiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Does not have kinase activity by itself.Post Translational Modifications: Phosphorylated on Ser-311 and, to a higher extent, on Ser-406 by MARK3. Dephosphorylated on Ser-406 by PPP2CA. In resting cells, phosphorylated KSR1 is cytoplasmic and in stimulated cells, dephosphorylated KSR1 is membrane-associated. Phosphorylated by PKA at Ser-888. Phosphorylation at Ser-888 is req |
Immunogen | Immunogen: A synthesized peptide derived from human KSR1 around the phosphorylation site of Ser569. |
Other Names | [BKSR 1; BKSR1; dKsr; EK 31; EK31; hb; Kinase suppressor of Ras 1; Kinase suppressor of ras; KSR 1; KSR; KSR1; KSR1_HUMAN; Positive Ras signaling mediator family member (86.4 kD); Positive Ras signaling mediator family member; RSU 2; RSU2; SR 31; SR31; Suppressor of activated let 60 Ras SUR3; Suppressor of Ras1 31] |
Gene, Accession # | [KSR1], Gene ID: 8844, NCBI: NP_055053.1, UniProt: Q8IVT5 |
Catalog # | MBS9610779 |
Price | $225, $280, $340 |
Order / More Info | Phospho-KSR1 (Ser569) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |