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Antigenic Specificity | Mad-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MAD1L1 is a component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. It recruits MAD2L1 to unattached kinetochores. Also it is required for anchoring MAD2L1 to the nuclear periphery. In addition, it binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding [PMID:10049595, 12837246]. |
Immunogen | Immunogen: Recombinant protein of human MAD1L1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [HsMAD1; MAD1; PIG9; TP53I9; TXBP181] |
Gene, Accession # | [Mad-1], Gene ID: 8379, NCBI: NP_001013858.1, UniProt: Q9Y6D9 |
Catalog # | MBS8502795 |
Price | $310 |
Order / More Info | Mad-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |