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Antigenic Specificity | CD33 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least three isoforms of CD33 are known to exist; this antibody will detect all three isoforms. CD33 Antibody: CD33 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family that is highly expressed on myeloid progenitor cells. Assessment of CD33 expression is of great importance in the immunodiagnosis of acute leukemia, allowing distinction between myeloid and lymphoid origin, as CD33 is generally restricted to the myelomonocytic lineage. CD33 can associate with the protein-tyrosine phosphatases SHP-1 and SHP-2 and thus could modulate downstream signaling events associated with cell activation. Common variants of CD33 have been found to be associated with late-onset Alzheimer's disease. |
Immunogen | Immunogen: CD33 antibody was raised against a 14 amino acid synthetic peptide near the center of human CD33. Buffer: CD33 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [CD33; p67; SIGLEC3; SIGLEC-3; Myeloid cell surface antigen CD33; Sialic acid-binding Ig-like lectin 3; Siglec-3; CD33 molecule], [CD33; CD33; p67; SIGLEC3; SIGLEC-3; SIGLEC3; Siglec-3] |
Gene, Accession # | [CD33], Gene ID: 945, NCBI: NP_001763, UniProt: P20138 |
Catalog # | MBS150613 |
Price | $375 |
Order / More Info | CD33 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |