CD33 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD33
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: At least three isoforms of CD33 are known to exist; this antibody will detect all three isoforms. CD33 Antibody: CD33 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family that is highly expressed on myeloid progenitor cells. Assessment of CD33 expression is of great importance in the immunodiagnosis of acute leukemia, allowing distinction between myeloid and lymphoid origin, as CD33 is generally restricted to the myelomonocytic lineage. CD33 can associate with the protein-tyrosine phosphatases SHP-1 and SHP-2 and thus could modulate downstream signaling events associated with cell activation. Common variants of CD33 have been found to be associated with late-onset Alzheimer's disease.
ImmunogenImmunogen: CD33 antibody was raised against a 14 amino acid synthetic peptide near the center of human CD33. Buffer: CD33 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[CD33; p67; SIGLEC3; SIGLEC-3; Myeloid cell surface antigen CD33; Sialic acid-binding Ig-like lectin 3; Siglec-3; CD33 molecule], [CD33; CD33; p67; SIGLEC3; SIGLEC-3; SIGLEC3; Siglec-3]
Gene, Accession #[CD33], Gene ID: 945, NCBI: NP_001763, UniProt: P20138
Catalog #MBS150613
Price$375
Order / More InfoCD33 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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