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Antigenic Specificity | Insulin Receptor (INSR) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. Mediates the metabolic functions of insulin. Binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. When present in a hybrid receptor with IGF1R, binds IGF1. |
Immunogen | n/a |
Other Names | [insulin receptor, partial; Insulin receptor; insulin receptor; insulin receptor; CD_antigen: CD220] |
Gene, Accession # | [INSR], Gene ID: 3643, NCBI: AAB30713.1 |
Catalog # | MBS8527309 |
Price | $310 |
Order / More Info | Insulin Receptor (INSR) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |