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Antigenic Specificity | DUSP10 (N-term), 1-30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: bovine) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DUSP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DUSP10. Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP10 binds to and |
Immunogen | n/a |
Other Names | [Dual specificity protein phosphatase 10; Mitogen-activated protein kinase phosphatase 5; MAP kinase phosphatase 5; MKP-5; DUSP10; MKP5] |
Gene, Accession # | [DUSP10], Gene ID: 11221, NCBI: NP_009138.1, UniProt: Q9Y6W6 |
Catalog # | MBS9213379 |
Price | $165, $370 |
Order / More Info | DUSP10 (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
Product Specific References | Tanoue, T., et al., J. Biol. Chem. 274(28):19949-19956 (1999). Theodosiou, A., et al., Oncogene 18(50):6981-6988 (1999). Martell, K.J., et al., Mol. Cells 8(1):2-11 (1998). Masuda, K., et al., Cytogenet. Cell Genet. 90 (1-2), 71-74 (2000) (): (). |