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Antigenic Specificity | ULBP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ULBP1 antibody is human and mouse specific. Multiple isoforms of ULBP1 are known to exist. The ULBPs are unusual members of the extended MHC class I superfamily because they do not contain the alpha 3 domain and they lack a transmembrane domain (1). They are known to bind to human NKG2D and activate multiple signaling pathways such as JAK2, STAT5, ERK and PI3K/Akt signal transduction pathways in NK / T cells, resulting in the production of cytokines and chemokines (2,3). ULBP1 is expressed on some tumor cells and has been implicated in tumor surveillance (4). |
Immunogen | Immunogen: ULBP1 antibody was raised against a 17 amino acid peptide near the center of human ULBP1. Buffer: ULBP1 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ULBP1; RAET1I; N2DL1; RAET1I; NKG2D ligand 1; ALCAN-beta; N2DL-1; UL16 binding protein 1], [ULBP1; ULBP1; RAET1I; N2DL1; RAET1I; N2DL-1; NKG2DL1] |
Gene, Accession # | [ULBP1], Gene ID: 80329, NCBI: NP_079494, UniProt: Q9BZM6 |
Catalog # | MBS153442 |
Price | $375 |
Order / More Info | ULBP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |