MAPK8 (T183/Y185), 159-195 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MAPK8 (T183/Y185), 159-195 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, rat, Xenopus) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.45 |
| Applications | ELISA (EIA), Immunohistochemistry-Paraffin(IHC-P), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAPK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-195 amino acids from human MAPK8. Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcripti |
| Immunogen | n/a |
| Other Names | [Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK8; JNK1; PRKM8; SAPK1; SAPK1C] |
| Gene, Accession # | [MAPK8], Gene ID: 5599, NCBI: NP_001265476.1, UniProt: P45983 |
| Catalog # | MBS9200829 |
| Price | $165, $370 |
| Order / More Info | MAPK8 (T183/Y185), 159-195 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Dasgupta, J., et al. J. Cell. Physiol. 225(1):52-62(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Gao, D., et al. J. Biol. Chem. 285(39):29965-29973(2010) Han, J.S., et al. Anticancer Res. 30(9):3407-3412(2010) Yang, X.H., et al. World J. Gastroenterol. 16(27):3385-3393(2010) |
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MYBIOSOURCE INC.
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