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Antigenic Specificity | IRF-5 |
Clone | [10T1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interferon regulatory factor 5 (IRF-5) is a member of IRF family, which plays a critical role in the regulation of genes induced by viral infection, immunostimulation and cell growth regulation. The expression of IRF-5 is limited to lymphoid organs, dendritic cells, and peripheral blood lymphocytes, but is not expressed in numerous leukemia and lymphoma cell lines. Three IRFs (IRF-3, IRF-5, IRF-7) function as direct transducers of virus-mediated signaling and play a critical role in the expression of type I interferon genes and some chemokines. |
Immunogen | Immunogen: Recombinant human IRF-5 (176-240aa) purified from E Coli. |
Other Names | [interferon regulatory factor 5; irf5], [IRF5; IRF5; SLEB10; IRF-5] |
Gene, Accession # | [IRF-5], Gene ID: 3663, NCBI: Q13568.2, UniProt: Q13568 |
Catalog # | MBS200481 |
Price | $255, $330 |
Order / More Info | IRF-5 Antibody from MYBIOSOURCE INC. |
Product Specific References | Mario B. et al. (2007) J. Virology 81(9):4473-4481. Ning S. et al. (2005) J. Virology 79:11671-11676. Mario B. et al. (2007) J. Virology 81(9):4473-4481. |