RB1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RB1 |
| Clone | [2A11D4] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Entrez Summary: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
| Immunogen | Immunogen: Purified recombinant fragment of human RB1 (AA: 2106-2784) expressed in E Coli. |
| Other Names | [RB; pRb; OSRC; pp110; p105-Rb], [RB; pRb; OSRC; pp110; p105-Rb] |
| Gene, Accession # | [RB1], Gene ID: 5925, NCBI: NP_000312.2, UniProt: P06400 |
| Catalog # | MBS476499 |
| Price | $335 |
| Order / More Info | RB1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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