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Antigenic Specificity | CD45R |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL (Concentrate), 7 mL (Prediluted), 1 mL (Concentrate) |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD45R, also known as MB1, is an isoform of CD45 that is a member of the protein tyrosine phosphatase (PTPase) family. CD45R is expressed specifically on the surface of hematopoietic cells, and has demonstrated function as a regulator of the antigen and cytokine receptor signalling of B and T cells. Given that the antigen is located in the membrane of all B cells, with the exception of plasma cells and some mature T cells, Anti-CD45R exhibits specific reactivity with most B lymphocytes. The use of Anti-CD45R is primarily useful in distinguishing B cell lymphomas from T cell lymphomas, with specific reactivity to follicle center cells, mantle cells, some medullary thymocytes, and 80% of B cell lymphomas. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [CD45R] |
Catalog # | MBS344103 |
Price | $165, $210, $270 |
Order / More Info | CD45R Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Myskow M, et al. Am J Clin Pathol. 1988; 90:564-74. 2. Shin S, et al. Hum Pathol. 1992; 23:686-94. |