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Antigenic Specificity | NBAS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NBAS antibody detects endogenous levels of total NBAS. Function: Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER (PubMed:19369418).Subunit Structure: Component of the NRZ complex composed of NBAS, ZW10 and RINT1/TIP20L; NRZ associates with SNAREs STX18, USE1L, BNIP1/SEC20L and SEC22B (the assembly has been described as syntaxin 18 complex); links NRZ to SNARE USE1L (PubMed:19369418). |
Immunogen | Immunogen: A synthesized peptide derived from human NBAS Subcellular Location: Endoplasmic Reticulum Tissue Specificity: Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblastoma cell lines. |
Other Names | [NBAS; NBAS_HUMAN; Neuroblastoma-amplified gene protein; Neuroblastoma-amplified sequence] |
Gene, Accession # | [NBAS], Gene ID: 51594, NCBI: NP_056993.2, UniProt: A2RRP1 |
Catalog # | MBS9610003 |
Price | $240, $280 |
Order / More Info | NBAS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |