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Antigenic Specificity | L3MBTL1 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This L3MBTL1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 451-485 amino acids from the Central region of human L3MBTL1. Polycomb group (PcG) protein that specifically recognizes and binds mono- and dimethyllysine residues on target proteins, therey acting as a 'reader' of a network of post- translational modifications. PcG proteins maintain the transcriptionally repressive state of genes: acts as a chromatin compaction factor by recognizing and binding mono- and dimethylated histone H1b/HIST1H1E at 'Lys-26' (H1bK26me1 and H1bK26me2) and histone H4 at 'Lys-20' (H4K20me1 and H4K20me2), leading to condense chromatin and repress transcription. Recognizes and binds p53/TP53 monomethylated at 'Lys- |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Lethal(3)malignant brain tumor-like protein 1; H-l(3)mbt; H-l(3)mbt protein; L(3)mbt-like; L(3)mbt protein homolog; L3MBTL1; L3MBTL1; KIAA0681; L3MBT; L3MBTL] |
Gene, Accession # | [L3MBTL1], Gene ID: 26013, NCBI: NP_056293.4, UniProt: Q9Y468 |
Catalog # | MBS9216318 |
Price | $165, $370 |
Order / More Info | L3MBTL1 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Koga H.,et al.Oncogene 18:3799-3809(1999).Ota T.,et al.Nat. Genet. 36:40-45(2004).Bechtel S.,et al.BMC Genomics 8:399-399(2007).Deloukas P.,et al.Nature 414:865-871(2001).Ishikawa K.,et al.DNA Res. 5:169-176(1998). |