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Antigenic Specificity | BRMS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 90-210 of human BRMS1 (NP 056214.1). |
Other Names | [breast cancer metastasis-suppressor 1 isoform 1; Breast cancer metastasis-suppressor 1; breast cancer metastasis-suppressor 1; BRMS1 transcriptional repressor and anoikis regulator] |
Gene, Accession # | [BRMS1], Gene ID: 25855, NCBI: NP_056214.1, UniProt: Q9HCU9 |
Catalog # | MBS8549658 |
Price | $280 |
Order / More Info | BRMS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |