Human IL-17A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman IL-17A
Clone[BL168]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatfluorescein (FITC) conjugate
Size20 tests, 50 tests, 100 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionIL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts; the enhancement of surface expression of ICAM-1 in fibroblasts; activation of NF-kappaB and costimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63%, 63%, and 72% amino acid sequence identity
Immunogenn/a
Other Names[CTLA8; IL17; CTLA-8; IL 17A]
Gene, Accession #[IL-17A], Gene ID: 3605, NCBI: NP_002181.1, UniProt: Q16552
Catalog #MBS2559221
Price$100, $125, $165
Order / More InfoHuman IL-17A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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