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Antigenic Specificity | Mouse CTLA-4 (CD152) |
Clone | [RYNmCTLA-4] |
Host Species | Hamster |
Reactive Species | n/a |
Isotype | IgG |
Format | ion exchange purified |
Size | 0.5 mg, 1 mg |
Concentration | 1mg/ml in PBS (after reconstitution). |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
Immunogen | Immunogen: mixture of mouse activated T cells. Antibody Properties: Blocking and staining antibody. For staining, use for blocking CTLA-4 function should be determined by the investigator. Available Conjugates: This antibody is only available as purified antibody. |
Other Names | [CTLA 4; CTLA-4 (CD152), Hamster Mouse; GSE; CD152; IDDM12; CELIAC3; CTLA-4], [CTLA4; CTLA4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; CD152; CTLA-4] |
Gene, Accession # | [CTLA-4], Gene ID: 1493, NCBI: NP_001032720.1 |
Catalog # | MBS140017 |
Price | $305, $455 |
Order / More Info | Mouse CTLA-4 (CD152) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |