Mouse CTLA-4 (CD152) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CTLA-4 (CD152)
Clone[RYNmCTLA-4]
Host SpeciesHamster
Reactive Speciesn/a
IsotypeIgG
Formation exchange purified
Size0.5 mg, 1 mg
Concentration1mg/ml in PBS (after reconstitution).
Applicationsn/a
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DescriptionIntroduction: CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
ImmunogenImmunogen: mixture of mouse activated T cells. Antibody Properties: Blocking and staining antibody. For staining, use for blocking CTLA-4 function should be determined by the investigator. Available Conjugates: This antibody is only available as purified antibody.
Other Names[CTLA 4; CTLA-4 (CD152), Hamster Mouse; GSE; CD152; IDDM12; CELIAC3; CTLA-4], [CTLA4; CTLA4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; CD152; CTLA-4]
Gene, Accession #[CTLA-4], Gene ID: 1493, NCBI: NP_001032720.1
Catalog #MBS140017
Price$305, $455
Order / More InfoMouse CTLA-4 (CD152) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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