SOX2 (Embryonic Stem Cell Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySOX2 (Embryonic Stem Cell Marker)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.
ImmunogenImmunogen: Recombinant fragment (within aa176-305) of human SOX2 protein (exact sequence is proprietary)
Other Names[ANOP3; Delta EF2a; MCOPS3 (Microphthalmia Syndromic type 3); SOX-2; SRY (sex determining region Y) box 2; SRY related HMG box 2; Transcription factor SOX-2; ysb]
Gene, Accession #[SOX2], Gene ID: 6657, NCBI: NP_003097.1, UniProt: P48431
Catalog #MBS4381255
Price$190, $340, $340
Order / More InfoSOX2 (Embryonic Stem Cell Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLaudet, V., et al, H. 1993. Nucleic Acids Res. 21: 2493-2501
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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