Human GFRA2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman GFRA2
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Size0.06 mL, 0.12 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionGFRA2 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. GFRA2 is a potent survival factor for central and peripheral neurons, and is essential for the development of kidneys and the enteric nervous system. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are its binding ligand which are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GDNF promotes the formation of a physical complex between GFRA/GDNFRa and the orphan tyrosin kinase receptor Ret, thereby inducing its tyrosine phosphorylation. The
ImmunogenImmunogen: Recombinant Human GFRA2 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose
Other Names[GDNF family receptor alpha-2 isoform c; GDNF family receptor alpha-2; GDNF family receptor alpha-2; GDNF family receptor alpha 2; GDNF receptor beta; GDNFR-beta; Neurturin receptor alpha; NRTNR-alpha; NTNR-alpha; RET ligand 2; TGF-beta-related neurotrophic factor receptor 2]
Gene, Accession #[GFRA2 ], Gene ID: 2675
Catalog #MBS2543936
Price$215, $330, $500
Order / More InfoHuman GFRA2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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