ATG3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ATG3 |
| Clone | [1377CT239.6.1.12] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1,k |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ATG3 antibody is generated from a mouse immunized with recombinant protein of human ATG3. E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12- ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8-like proteins. The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). Preferred substrate i |
| Immunogen | n/a |
| Other Names | [Ubiquitin-like-conjugating enzyme ATG3; 632-; Autophagy-related protein 3; APG3-like; hApg3; Protein PC3-96; ATG3; APG3; APG3L] |
| Gene, Accession # | [ATG3], Gene ID: 64422, NCBI: NP_001265641.1, UniProt: Q9NT62 |
| Catalog # | MBS9200107 |
| Price | $165, $370 |
| Order / More Info | ATG3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Tanida I.,et al.J. Biol. Chem. 277:13739-13744(2002). Wu B.X.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases. Bechtel S.,et al.BMC Genomics 8:399-399(2007). Ota T.,et al.Nat. Genet. 36:40-45(2004). Tanida I.,et al.Biochem. Biophys. Res. Commun. 296:1164-1170(2002). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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