NGAL (Capture Ab) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNGAL (Capture Ab)
Clone[H11]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein A purified
Size1 mg
Concentration5 mg/ml
ApplicationsWestern Blot (WB), Lateral Flow (LF), ELISA (EIA)
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DescriptionSpecificity: It specifically recognize the human NGAL. Lipocalin-2 (LCN2), also known as oncogene 24p3 or neutrophil gelatinase-associated lipocalin (NGAL), is a protein associated with neutrophil gelatinase. The 25-kD LCN2 protein is believed to bind small lipophilic substances such as bacteria-derived lipopolysaccharide (LPS) and formylpeptides and may function as a modulator of inflammation. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor.
ImmunogenImmunogen: Recombinant human NGAL.
Other Names[NGAL (Capture Ab)], [LCN2; LCN2; 24p3; MSFI; NGAL; HNL; NGAL; NGAL]
Gene, Accession #[NGAL], Gene ID: 3934, NCBI: NP_005555.2, UniProt: P80188
Catalog #MBS355004
Price$520
Order / More InfoNGAL (Capture Ab) Antibody from MYBIOSOURCE INC.
Product Specific References1. Kjeldsen, L., Johnsen, A. H., Sengelov, H., Borregaard, N. Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. J. Biol. Chem. 268: 10425-10432, 1993. 2. Flo TH, Smith KD, Sato S, Rodriguez DJ, Holmes MA, Strong RK, Akira S, Aderem A (December 2004). Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature 432 (7019): 917-21. 3. Schmidt-Ott KM, Mori K, Li JY, Kalandadze A, Cohen DJ, Devarajan P, Barasch J (February 2007). Dual action of neutrophil gelatinase-associated lipocalin. J. Am. Soc. Nephrol. 18 (2): 407-13.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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