Edit |   |
---|---|
Antigenic Specificity | GCN2 (Phospho Thr899) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-GCN2 (T899) Polyclonal Antibody detects endogenous levels of GCN2 protein only when phosphorylated at T899. EIF2AK4 encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the down regulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. |
Immunogen | Immunogen: Synthesized peptide derived from human GCN2 around the phosphorylation site of T899 |
Other Names | [Rabbit GCN2 (phospho Thr899); EIF2AK4; GCN2; KIAA1338; Eukaryotic translation initiation factor 2-alpha kinase 4; GCN2-like protein] |
Gene, Accession # | [GCN2], Gene ID: 440275, NCBI: Q9P2K8.3, UniProt: Q9P2K8 |
Catalog # | MBS9705905 |
Price | $130, $220, $325 |
Order / More Info | GCN2 (Phospho Thr899) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |