beta-Catenin Antibody Sampler Kit Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-beta-Catenin Antibody Sampler Kit antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | beta-Catenin Antibody Sampler Kit |
| Clone | n/a |
| Host Species | n/a |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 1 kit |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: beta-Catenin is a key downstream effector in the Wnt signaling pathway. It is implicated in two major biological processes in vertebrates: early embryonic development and tumorigenesis. CK1 phosphorylates beta- catenin at Ser45. This phosphorylation event primes beta-catenin for subsequent phosphorylation by GSK-3beta. GSK-3beta destabilizes beta-catenin by phosphorylating it at Ser33, Ser37, and Thr41. Mutations at these sites result in the stabilization of beta-catenin protein levels and have been found in many tumor cell lines. Both Akt and PKA were shown to phosphorylate beta-catenin at Ser552 and Ser675. Phosphorylation at Ser552 and Ser675 induces beta-catenin accumulation in the nucleus and increases its transcriptional a |
| Immunogen | n/a |
| Other Names | [beta-catenin; beta-catenin] |
| Gene, Accession # | Gene ID: 445806, NCBI: NP_001027779.1 |
| Catalog # | MBS2550014 |
| Price | $345 |
| Order / More Info | beta-Catenin Antibody Sampler Kit Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies