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Antigenic Specificity | Gle1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Gle1 Antibody: The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist. |
Immunogen | Immunogen: Gle1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human Gle1. Buffer: Gle1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Gle1; LCCS; GLE1L; LCCS1; hGLE1; Nucleoporin GLE1; GLE1-like protein; GLE1 RNA export mediator homolog (yeast)], [GLE1; GLE1; LCCS; GLE1L; LCCS1; hGLE1; GLE1L; hGLE1] |
Gene, Accession # | [GLE1], Gene ID: 2733, NCBI: NP_001003722, UniProt: Q53GS7 |
Catalog # | MBS150335 |
Price | $375 |
Order / More Info | Gle1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |