CIB1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CIB1 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 1ug/ul |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CIB1 (also designated calcium and integrin binding 1 or calmyrin), with 191-amino acid protein (about 21kDa), belongs to the calcium-binding protein family. CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha (IIb)beta (3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha (IIb) cytoplasmic domain of platelet integrin alpha (IIb)beta (3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R. |
| Immunogen | Immunogen: Ni-NTA purified truncated recombinant CIB1 expressed in E Coli strain BL21 (DE3) |
| Other Names | [calcium and integrin-binding protein 1 isoform a; Calcium and integrin-binding protein 1; calcium and integrin-binding protein 1; calcium and integrin binding 1; Calcium- and integrin-binding protein; CIBP; Calmyrin; DNA-PKcs-interacting protein; Kinase-interacting protein; KIP; SNK-interacting protein 2-28; SIP2-28], [CIB1; CIB1; CIB; CIBP; KIP1; PRKDCIP; SIP2-28; CIB; KIP; PRKDCIP; CIB; CIBP; KIP; SIP2-28] |
| Gene, Accession # | [CIB1], Gene ID: 10519, NCBI: NP_001264693.1, UniProt: Q99828 |
| Catalog # | MBS418379 |
| Price | $445 |
| Order / More Info | CIB1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Holly R. Gentry, Alex U. Singer, Laurie Betts J. Biol. Chem., Mar 2005; 280: 8407 - 8415. 2. Carl White, Jun Yang, Mervyn J. Monteiro J. Biol. Chem., Jul 2006; 281: 20825 - 20833 3. Aaron P. Yamniuk, Hiroaki Ishida, Hans J. Vogel J. Biol. Chem., Jul 2006; 10.1074/jbc.M603963200. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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