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Antigenic Specificity | Human CXADR |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 107 aa intracellular domain, among which, D1 is thought to be responsible for homodimer formation in trans |
Immunogen | Immunogen: Recombinant Human CXADR protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
Other Names | [coxsackievirus and adenovirus receptor; Coxsackievirus and adenovirus receptor; coxsackievirus and adenovirus receptor; coxsackie virus and adenovirus receptor; CVB3-binding protein; Coxsackievirus B-adenovirus receptor; HCVADR] |
Gene, Accession # | [CXADR ], Gene ID: 1525 |
Catalog # | MBS2544078 |
Price | $215, $330, $500 |
Order / More Info | Human CXADR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |