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Antigenic Specificity | AP2 alpha (N-term), 104-133 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.45 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This AP2 alpha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human AP2 alpha. Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. |
Immunogen | n/a |
Other Names | [Transcription factor AP-2-alpha; AP2-alpha; AP-2 transcription factor; Activating enhancer-binding protein 2-alpha; Activator protein 2; AP-2; TFAP2A; AP2TF; TFAP2] |
Gene, Accession # | [TFAP2A], Gene ID: 7020, NCBI: NP_001027451.1, UniProt: P05549 |
Catalog # | MBS9202589 |
Price | $165, $370 |
Order / More Info | AP2 alpha (N-term), 104-133 Antibody from MYBIOSOURCE INC. |
Product Specific References | Provenzano,M.J., Exp. Mol. Pathol. 83 (2), 277-282 (2007) Tan,Y.R., Biochem. J. 405 (1), 131-137 (2007) Liu,H., EMBO Rep. 8 (4), 394-400 (2007) Han,S., J. Biol. Chem. 282 (11), 7961-7972 (2007) |