WAC Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | WAC |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: At least two isoforms of WAC are known to exist; this antibody will detect the larger isoform. WAC Antibody: The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35. Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination. WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites. WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress. |
| Immunogen | Immunogen: WAC antibody was raised against a 19 amino acid peptide near the center of human WAC. Buffer: WAC Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [WAC; Wwp4; BM-016; PRO1741; KIAA1844; WW domain-containing adapter protein with coiled-coil; WW domain containing adaptor with coiled-coil], [WAC; WAC; Wwp4; BM-016; PRO1741; KIAA1844] |
| Gene, Accession # | [WAC], Gene ID: 51322, NCBI: NP_057712, UniProt: Q9BTA9 |
| Catalog # | MBS153531 |
| Price | $375 |
| Order / More Info | WAC Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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